What is the lack of pyruvat kinase?
The lack of pyruvate kinase is the lack of enzyme pyruvate kinase. This enzyme is used by red blood cells to keep them strong. Without the pyruvate kinase enzyme, red blood cells are easier to disintegrate than they should. If too many red blood cells are destroyed, one may suffer from anemia, a lack of oxygen in the blood that leads to weakness, fatigue and other symptoms.
When the red blood cells are pumped through the lungs, they collect oxygen, which they then relax as they travel on the rest of the body. Most organs in the human body need oxygen to work properly. In people with a lack of pyruvate kinase, red blood cells break down too easily. Soon there is not enough blood cells to deliver the necessary oxygen.
The lack of pyruvat kinase can lead to serious complications. The most serious of these is hemolytic anemia, a form of anemia, which is the result of too many red blood cells that break down too quickly. Products of the decomposition of cells Buzse in blood and urine, causing darkUrine and jaundice, yellowing of the skin and white eyes. If it is not treated, hemolytic anemia can lead to organ failure, especially the heart. The lack of pyruvate kinase is the second most common cause of haemolytic anemia.
people who have a lack of pyruvat kinases can also obtain bile stones that continue to appear after treatment. The gallstones are small rock mass, which is formed from the gastrointestinal gallbladder. They can cause inflammation and infection. Bile stones can be treated either by oral medicines or surgery. Most people are able to have their gallbladder removed without causing any health complications.
The lack of pyruvate kinase does not necessarily mean that the affected person will suffer from serious symptoms. Some people live a relatively normal and healthy life. Less serious symptoms of pyruvate kinase deficiency include fatigue, pale skin and mild jaundice.
those who are roThey involve serious health problems caused by a lack of pyruvate kinase, they can help splenectomy. Removing the spleen tends to slow down the destruction of red blood cells, although it does not work in all patients. Blood transfusions can also help those with severe anemia.
The lack of pyruvate kinase is a recessive feature. Both parents must therefore have a defective form of the gene to give it to their child. It occurs in people of all different ethnicities around the world.