What Is Serotonin Deficiency?

Serotonin is a neurotransmitter produced in the body and is found in some plants and fungi. But there are works that show that there are nutrients involved in the synthesis of serotonin. These nutrients include tryptophan (an amino acid), omega-3 fatty acids, magnesium and zinc.

Serotonin

Serotonin is a neurotransmitter produced in the body and is found in some plants and fungi. However, some works have shown that there are nutrients that can participate in the synthesis of serotonin. These nutrients include tryptophan (an amino acid), omega -3

Neurotransmitter is a mixed substance used by nerve cells to transmit information to each other. This means that nerves use serotonin as a channel to communicate with each other and transmit information. Some nerve cells use serotonin, while other nerve cells can use different neurotransmitters. Serotonin affects appetite, drive (appetite, sleep, sex) and mood. ^[1]

Properly increasing the serotonin content through diet can improve sleep, make people calm, reduce irritability, bring joy and happiness, and bring people more happiness.

Some animal experiments have shown that when 5-HT content is increased in animals, the mutual attack behavior of animals is significantly reduced.

See entry for serotonin.

Serotonin is currently known to be involved in controlling gastrointestinal motility, sensitivity, and secretion, so serotonin has become a potential therapeutic drug for gastrointestinal diseases. There are currently 14 known serotonin receptors, of which 5-HT1A agonist 5-HT1B / D agonist 5-HT2A antagonist 5-HT3 antagonist and 5-HT4 agonist are used clinically to treat various diseases .

Serotonin is an indole derivative. Molecular formula C10H12N2O. It is ubiquitous in plant and animal tissues. Serotonin can interact with acids to form crystalline salts. Its hydrochloride has a melting point of 167 to 168 ° C; its picrate has a melting point of 185 to 189 ° C. Serotonin has a higher concentration in brain tissue, and it is an important substance that regulates nerve activity. Some body tissues can release serotonin when exposed to certain drugs, such as a

Many health problems are related to low levels of serotonin in the brain. There are many reasons for the reduction in serotonin, including stress, lack of sleep, malnutrition and lack of exercise. When it is reduced below the required level, people will have problems such as difficulty concentrating, which will indirectly affect personal planning and organizational capabilities. This condition is often accompanied by stress and boredom, and can cause depression if serotonin levels decrease further.

Other problems related to lowered brain serotonin levels include irritability, anxiety, fatigue, chronic pain, and restlessness. If precautions are not taken, these problems can worsen over time and eventually cause

It is important to maintain a balanced serotonin level in the brain. When serotonin is insufficient, it is necessary to supplement in time. Methods to increase this neurotransmitter include:

People often use "angry to lose their sense of anger" to describe a person's anger. In fact, it is not necessarily that the brain has no sense, but may be that the responsible part of the brain lacks a signal substance, serotonin, It is therefore difficult to control the activity of the brain parts associated with anger.

Nerve cells need to communicate information with the help of serotonin.

At the beginning of 2013 ^[2] , Xu Huaqiang's group and Jiang Hualiang's group of Shanghai Institute of Materia Medica, Chinese Academy of Sciences cooperated with researchers at The Scripps Research Institute and the University of North Carolina in Important progress has been made in ligand recognition mechanisms. The two research papers will be published in Science, March 22, 2013, Beijing time.

Xu Huaqiang and others also collaborated with Jiang Hualiang's group to use computational biology to systematically summarize the ligand recognition mechanism of the serotonin receptor system, and elaborated the molecular mechanism of serotonin receptor-ligand binding. Based on the structure determination, they also cooperated with Bryan Roth of the University of North Carolina in the United States. Using point mutations and analysis of downstream signaling, they revealed the signaling specificity of the serotonin receptor subtype. ^[3]