What Is Skeletal Dysplasia?

Skeletal dysplasia (SD) is a genetic disease that affects the composition and structure of bone and cartilage tissue. Clinical manifestations are abnormal growth and development of various skeletal tissues, such as short stature, joint dislocation, deformities of the skull and limbs, and spinal curvature Abnormalities, changes in bone density, etc., sometimes combined with other system deformities. In 1986, Stoll et al. Reported epidemiological statistical analysis and a summary of previous studies and reported that the prevalence of SD in birth was about 3/10000, and proposed that ultrasound examination is a feasible method for prenatal diagnosis.