What is Thalassemia the main?
Thalassemia Major, also known as beta Thalassemia, or Cooley's anemia, is a genetic blood disorder that causes the body to produce an abnormal form of hemoglobin. Hemoglobin is a protein molecule in red blood cells that bears oxygen. Thalassemia is the main thing when the production of beta globin protein is affected by gene defects, resulting in destruction of red blood cells and anemia.
In order to develop blood disorder, patients must inherit the defective gene from both parents. Cresh thalassemia occurs when the patient inherits only one defective gene. Patients diagnosed with thalasemia minors do not show symptoms and are simply carriers of a defective gene. African Americans and Asians, especially the Chinese, are also genetically predisposed to blood disorder. Prenatal screenings and genetic counseling are available to those who are afraid of families of disease history.
When a child is born with a major thalassymia, the diagnosis is not always obvious until the child develops anemia, usually during the firstthe year of life. The symptoms of thalassymia, which the parent may notice, include stir, poor appetite and increased infection. As the child ripens, other symptoms may include delayed growth, bone deformities into the face and extended abdomen caused by swelling of the liver and spleen. Without treatment, blood disorder can lead to heart failure and jar problems.
Thalassemia is diagnosed using blood tests. The complete blood count (CBC) identifies anemia, while smaller than average red blood cells and other abnormalities that are characteristic of blood disorder can be seen under the microscope. Another test called hemoglobin electrophoresis helps further identify abnormal hemoglobin, which is typical of this type of Thalassemia.
The most common treatment of Major Thalassymia is the regime of regular blood transfusions. Patients are often prescribed another medicine called chelating therapy to reduce the damageThe effects of transfusion because they can cause abnormal iron accumulation in the body. Most patients are also recommended to take daily doses of folic acid. Bone marrow transplantation may be in some patients, especially children, and those who have full siblings who can serve as corresponding bone marrow donors can be a viable treatment. Although these treatment options have improved prognosis for many patients, long -term survival remains a challenge for those who are affected by serious cases of disease.