What Is Thalassemia Major?

The thalassemia gene is the direct cause of thalassemia. Thalassemia is a group of hereditary disorders caused by hereditary peptide synthesis. The parents of thalassemia patients are often mild thalassemia patients. It can also be said that the pathological gene carriers each have a pathological gene. If the parents' genetic genes are inherited to their children at the same time, the children have two pathological genes. In China, the a-thalassaemia gene carrier rate is 2.64%.

Thalassemia gene

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Registration Number	State Food and Drug Administration (quasi) word 2013 No. 3401572	product name	- and -type thalassemia gene detection kit (PCR-hybridization method)
Production unit	Beijing Hyundai Gundam Biotechnology Co., Ltd.	address	Building 4, No. 7 A, Yongchang North Road, Beijing Economic and Technological Development Zone, Beijing
Product Standards	YZB / National 5324-2013	Product performance structure and composition	This kit consists of two parts: Part I (-20 ° C, protected from light), which contains: PCR mix A (Taq enzyme, UNG, primer, dNTP) (1.15mL / tube, white, 1 tube); PCR mixB (Taq Enzyme, UNG, primer, dNTP) (1.15 mL / tube, white, 1 tube); mutation control A (mutation + wild type plasmid DNA) (50 L / tube, red, 1 tube); deletion control B (deletion + wild type) Plasmid DNA) (50 L / tube, red, 1 tube); blank control (purified water, PCR only) (1 mL / tube, natural color, 1 tube). Part II (stored at 2-8 ° C and protected from light), containing: multiple microbead hybridization solution (microbeads labeled with probes) (1.2mL / tube, green, 2 tubes); color development mother liquor (SAPE) (10L / tube, (Yellow, 1 tube); chromogenic dilution solution (TMAC) (1.75mL / tube, blue, 2 tubes); 10 × washing solution (PBS-T) (1.75mL / tube, white, 2 tubes); detection solution ( TE) (1.5 mL / tube, white, 2 tubes); hybridization blank control (purified water, special for hybridization) (1 mL / tube, natural color, 1 tube). Instructions (1 copy). Product expiration date: Part (I) of the kit is stored in the dark at -20 ° C, and part (II) is stored in the dark at 2-8 ° C. The expiration date is 12 months. Attachment: Registered product standards, product manuals.
The scope of products	This product is suitable for the qualitative detection of thalassemia genotypes in human whole blood genomic DNA samples (see the instruction manual for specific genotype types in Table 1). It contains 3 alpha mutations, 3 alpha deletions, and 17 beta mutations. ).	Specifications	48 servings / box
Approval date	2013.10.10	Expiration date	2017.10.09
Change date		Production site	Beijing Economic and Technological Development Zone, Beijing, No. 7 A, Yongchang North Road 4; Beijing Economic and Technological Development Zone, Ludong District, East Road, No. 88, Kechuang 6th Street, Enterprise Building A3, Room A1-1.

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