What is the amyloidosis of transthyretin?
transthyretin amyloidosis is a inherited condition that causes the accumulation of abnormal proteins in the body called amyloids. They may begin to interfere with the patient's nervous system and cause progressive symptoms. The age of start can range from 20 to 70, depending on the specific mutations involved and tend to be previously in people who come from regions with a long history of illness such as Portugal and Japan. Treatment options are available and tend to be the most effective when they are provided early. It normally acts as a transporter for hormones of vitamin A and thyroid gland and begins to transmit amyloid deposits to the nervous system where it is built over time. There are three forms of disease: leptomening, peripheral and heart. These forms are named for different areas of the body that affect.
in patients Sltomeningeal Transstyretin amyloidosis, amyloids are formed in the central nervous system while peripheral patients experience symptoms in the peripheral nervous system, such as dullness, armor and loss of engine control. Cardiac forms attack heart muscles and cause irregular heart rhythm. Some testing can determine which form the patient has and identify rogue proteins responsible for learning more about the origin of the state.
Some medicines are available to treat patients with transthyretin amyloidosis. Another option is to transplant liver, especially if it is provided early. The new liver does not carry a defective gene and should encodhyretin correctly. In patients with existing amyloidosis, these effects will not be reversed, but the progression of the disease may stop. Other patients may continue to have problems as amyloids can continue to be used without a supporting protein for some BVs.
gene for this condition is dominant. Someone has to inherit one copy to express it, and the parent with the disease has 50% chance to pass it to the child or 100% chance if youThe parent accidentally carried two copies of the gene. Parents who are worried about transtyretin amyloidosis may encounter a genetic advisor to get more information about their possibilities. This may include some testing to find out more about their genetics, as this could provide useful information on how to manage the risks of genetic diseases such as transtyretin amyloidosis in children.