What Factors Affect Lactulose Dosage?

Lactulose, also known as 4-O--D-galactopyranosyl-D-fructose, is a disaccharide composed of galactose and fructose, which does not exist in nature. Lactulose generally appears as a syrupy product. Lactulose has important physiological and pharmacological functions, and is widely used in clinical medicine, health products and food additives.

Chinese name

Chinese alias: 4-O--D-Galactopyranosyl-D-fructofuranose; Isomerized lactose solution;

English name: lactulose

English alias: laevolac; Lactulose; Cholac; Enulose; Liforos;

CAS number: 4618-18-2

Molecular formula: C ₁₂ H ₂₂ O ₁₁

Molecular weight: 342.29600

Structural formula:

Appearance and properties: white powder

Density: 1.32 g / cm3

Melting point: 169 ° C (dec.)

Boiling point: 680.5ºC at 760 mmHg

Flash point: 365.4ºC

Refractive index: 1.45-1.47

Water solubility: 76.4 G / 100 ML (30 ºC)

Storage conditions: refrigerated

Lactulose chemical name 4-O--D-galactopyranosyl-D-fructose, molecular weight 342, and lactose is

1.Chemical method

Alkali single catalysis: This system mainly uses sodium hydroxide,

Lactulose slowly induces diarrhea through infiltration and physical action in the colon, and has no or little effect on the intestinal flora, pH, and electrolytes, so it is effective and safe for chronic functional constipation. Lactulose can block ammonia absorption, especially in patients with liver disease, but it is contraindicated in those with gastrointestinal obstruction.