What Is Mibefradil?
The name of the drug melbladil, which is a new selective T-type calcium channel blocker. It selectively and competitively blocks T-type calcium channels, which makes coronary arteries dilate and relax vascular smooth muscle. It has no inhibitory effect on myocardial contraction, can inhibit sinoatrial nodes, and slow heart rate. Not accompanied by changes in reflex neurotransmitter excitation and hormone secretion activity. Animal tests have shown that mibeladil can block the L-type calcium channels of the heart and blood vessels, and can block the release of intracellular calcium ions.