What is Histidin?
histidine is one of 22 amino acids derived from high protein foods and also from certain grains. It is one of the aromatic amino acids that are becoming an essential amino acid in human infants, but later become an insignificant amino acid when the body begins to synthesize from imidazole, organic compounds and components of the aromatic circle in the chemical structure of acid. Histidine is also a precursor of some amino and amino acid peptides such as histamine and carnosine. The complete chemical name of this substance is written as 2-amino-3- (1h-imidazole-4-yeh) propane, but it is often shortened to L-Histidin, or simply "H". It is the key to the formation of myelin sheath, a protective barrier that surrounds nerve cells and promotes the transfer of brain signals to various parts. It will also participate in detoxification of heavy metals and other cellular residues for elimination through liver and kidneys. This substance is essential for the body to produce white and red blood cells. And finally, since this acid is involved in histamine production, it plays a role in creating stomach enzymes needed for proper digestion, helping the immune system in response to the presence of allergens and supporting normal sexual function.
l-historidine is necessary to allow the body to metabolize many trace minerals, including iron, zinc, copper and manganese. For example, in terms of iron use, it is necessary to produce ferritin and "fur", otherwise known as the protein for iron storage and protein control of iron absorption. Histidin is also needed to produce various enzymes such as antioxidant super oxide desmutaz.
There are evidence that indicates that low levels of histidine or impaired metabolism can be associated with various disorders. For example, scientists suspect that a deficiency may lead to an increased risk of developing rheumatoid arthritis in some people. Abnormally low levelsThey were also associated with the loss of hearing after injury as a result of specialized myeline capsule cells called the "Schwann cell", which could not start repairing damaged nerves. On the other hand, the high levels of this amino acid were associated with greater prevalence of depression and anxiety disorders, as well as schizophrenia.
In supplementation, this amino acid may benefit an individual, in others it is contraindicated. On the one hand, its effects on the central nervous system and histamine regulation suggest that people with depressive disorders should avoid it unless the doctor is directed otherwise. In addition, people with kidney or liver disorders should not take this amino acid in the form of a supplement.