What are different types of PKD?
Polycystic kidney disease, commonly referred to as PKD or PCKD, is a genetic condition in which the kidneys develop more cysts. The cyst is an abnormal bag in which gas, liquid or semi -solid material are closed. Cysts that occur as a result of PKD are filled with liquid, differ in size and cause dramatic enlargement of the kidneys. Although it primarily affects the kidneys, PKD can also create cysts in the liver, colon and pancreatic and damage blood vessels, heart and brain. There are two types of PKD, autosomal dominant and autosomal recessive. These organs are responsible for the production of urine, blood filtering, reabsorption of sugars and salt into the bloodstream and control of the water concentration of the body, among other things. The kidneys of PKD patients gradually lose their ability to perform these functions, sometimes by the culmination of kidney failure. Usually, it takes many years. Symptoms that may develop include high blood pressure, headaches, blood in the urine, kidney stones, rear or lateral pain, swelling of the abdomen, frequent MOImpressing, infection in the urinary tract or kidneys and at the end of kidney failure. In the case of renal failure, patients may require transplant or kidney dialysis, which is an artificial replacement for kidney function.
Two types of PKD, autosomal dominant and autosomal recessive are divided on the basis of various genetic defects that cause PKD. The autosomal dominant polycystic kidney disease (ADPKD) is by far the more common of the two. This defect is handed over to the dominant gene, so if one parent has this disease, the child also has a fifty percent chance of developing a disorder. In the past, ADPKD was called an adult PKD, because it often preliminary nations NTS aged thirty and forty years. However, children can also develop an autosomal dominant PKD.
A defect that causes autosomal recessive polycystic kidney disease (Arpkd) is released by a recessive gene. Because the gene is recessive if the poisonEN The parent carries a defect and the other parent does not, the defective gene will be rewritten by a healthy gene. However, if both parents bear an unusual recessive gene, the child has twenty -five percent of the chance to develop Arpkd. Unlike ADPKD, which may come from one of two possible defective genes, only one gene is associated with the ARPKD. Symptoms of Arpkd usually occur in childhood, but do not have to evolve until late childhood or early adolescent years.
The doctor may unintentionally discover PKD or intentionally search for PKD using imaging technology. Usually these tests include ultrasonic scan, computer tomography (CT) scanning or scanning by magnetic resonance (MRI). In some cases, specifics, when a family member donates kidneys, genetic testing may also be included in the diagnostic phase. Treatment of symptoms and complications of PKD will then be determined on the basis of the size, number and location of the cysts and symptoms experienced by the patient. Treatment may include medicines to control blood pressure, surgery to drain cysts, antibiotic treatment of infections, painkillers and continued monitoring of affected areas.