What Is Factor V Leiden?

Factor V Leiden (FVL) is a mutation of the fifth factor gene. Leiden's fifth factor mutation rate is very high. Because Leiden's fifth factor is abnormal, it can't block blood coagulation function and cause clotting abnormality to form embolism. People who carry Leiden factor V are five times more likely to develop blood clots than those who do not. However, there are still many people who carry this gene who never get sick. The fifth factor of Leiden is named after the Dutch city of Leiden, where Professor R. Bertina was identified in 1994.

Leiden factor

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Factor V Leiden (FVL) is a mutation of the fifth factor gene. Leiden's fifth factor mutation rate is very high. Because Leiden's fifth factor is abnormal, it can't block blood coagulation function and cause clotting abnormality to form embolism. People who carry Leiden factor V are five times more likely to develop blood clots than those who do not. However, there are still many people who carry this gene who never get sick. The fifth factor of Leiden is named after the Dutch city of Leiden, where Professor R. Bertina was identified in 1994.